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Nutrition in children with exocrine pancreatic insufficiency
Exocrine pancreatic insufficiency (EPI) is a condition defined as pancreatic loss of exocrine function, including decreased digestive enzymes and bicarbonate secretion, which leads to maldigestion and malabsorption of nutrients. It is a common complication in many pancreatic disorders. If left undia...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196508/ https://www.ncbi.nlm.nih.gov/pubmed/37215591 http://dx.doi.org/10.3389/fped.2023.943649 |
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author | Zheng, Yuhua Mostamand, Shikib |
author_facet | Zheng, Yuhua Mostamand, Shikib |
author_sort | Zheng, Yuhua |
collection | PubMed |
description | Exocrine pancreatic insufficiency (EPI) is a condition defined as pancreatic loss of exocrine function, including decreased digestive enzymes and bicarbonate secretion, which leads to maldigestion and malabsorption of nutrients. It is a common complication in many pancreatic disorders. If left undiagnosed, EPI can cause poor digestion of food, chronic diarrhea, severe malnutrition and related complications. Nutritional status and fat-soluble vitamins should be carefully assessed and monitored in patients with EPI. Early diagnosis of EPI is clinically important for appropriate nutritional support and initiating pancreatic enzyme replacement therapy (PERT) which could significantly improve patient outcomes. The evaluation of nutritional status and related unique management in children with EPI will be discussed in this review. |
format | Online Article Text |
id | pubmed-10196508 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-101965082023-05-20 Nutrition in children with exocrine pancreatic insufficiency Zheng, Yuhua Mostamand, Shikib Front Pediatr Pediatrics Exocrine pancreatic insufficiency (EPI) is a condition defined as pancreatic loss of exocrine function, including decreased digestive enzymes and bicarbonate secretion, which leads to maldigestion and malabsorption of nutrients. It is a common complication in many pancreatic disorders. If left undiagnosed, EPI can cause poor digestion of food, chronic diarrhea, severe malnutrition and related complications. Nutritional status and fat-soluble vitamins should be carefully assessed and monitored in patients with EPI. Early diagnosis of EPI is clinically important for appropriate nutritional support and initiating pancreatic enzyme replacement therapy (PERT) which could significantly improve patient outcomes. The evaluation of nutritional status and related unique management in children with EPI will be discussed in this review. Frontiers Media S.A. 2023-05-05 /pmc/articles/PMC10196508/ /pubmed/37215591 http://dx.doi.org/10.3389/fped.2023.943649 Text en © 2023 Zheng and Mostamand. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Pediatrics Zheng, Yuhua Mostamand, Shikib Nutrition in children with exocrine pancreatic insufficiency |
title | Nutrition in children with exocrine pancreatic insufficiency |
title_full | Nutrition in children with exocrine pancreatic insufficiency |
title_fullStr | Nutrition in children with exocrine pancreatic insufficiency |
title_full_unstemmed | Nutrition in children with exocrine pancreatic insufficiency |
title_short | Nutrition in children with exocrine pancreatic insufficiency |
title_sort | nutrition in children with exocrine pancreatic insufficiency |
topic | Pediatrics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196508/ https://www.ncbi.nlm.nih.gov/pubmed/37215591 http://dx.doi.org/10.3389/fped.2023.943649 |
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