Deciphering the Clinical Significance and Kinase Functions of GSK3α in Colon Cancer by Proteomics and Phosphoproteomics

GSK3α and GSK3β are two GSK3 isoforms with 84% overall identity and 98% identity in their catalytic domains. GSK3β plays important roles in the pathogenesis of cancer, while GSK3α has long been considered a functionally redundant protein of GSK3β. Few studies have specifically investigated the funct...

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Detalles Bibliográficos
Autores principales: Gao, Li, Lu, Ying, Chen, Hai-Ning, Li, Zhigui, Hu, Meng, Zhang, Rou, Wang, Xiuxuan, Xu, Zhiqiang, Gong, Yanqiu, Wang, Rui, Du, Dan, Hai, Shan, Li, Shuangqing, Su, Dan, Li, Yuan, Xu, Heng, Zhou, Zong-Guang, Dai, Lunzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article Collection: Cancer Proteomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196724/
https://www.ncbi.nlm.nih.gov/pubmed/37031867
http://dx.doi.org/10.1016/j.mcpro.2023.100545

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