Mitochondrial translational defect extends lifespan in C. elegans by activating UPR(mt)

Aminoacyl-tRNA synthetases (aaRSs) are indispensable players in translation. Usually, two or three genes encode cytoplasmic and mitochondrial threonyl-tRNA synthetases (ThrRSs) in eukaryotes. Here, we reported that Caenorhabditis elegans harbors only one tars-1, generating cytoplasmic and mitochondr...

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Detalles Bibliográficos
Autores principales: Guo, Miaomiao, Qiao, Xinhua, Wang, Yuanyuan, Li, Zi-Han, Shi, Chang, Chen, Yun, Kang, Lu, Chen, Chang, Zhou, Xiao-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196762/
https://www.ncbi.nlm.nih.gov/pubmed/37167879
http://dx.doi.org/10.1016/j.redox.2023.102722

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196762/
https://www.ncbi.nlm.nih.gov/pubmed/37167879
http://dx.doi.org/10.1016/j.redox.2023.102722

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