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Oxymatrine blocks the NLRP3 inflammasome pathway, partly downregulating the inflammatory responses of M1 macrophages differentiated from THP-1 monocytes()

Many chronic inflammatory diseases, such as autoimmune inflammation, are associated with M1 macrophages, and the key to their treatment is blocking inflammation. Oxymatrine (OMT), a traditional Chinese medicine, has a marked anti-inflammatory effect. However, its anti-inflammatory target and mechani...

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Detalles Bibliográficos
Autores principales:	Zhang, Ke, Liu, Youyang, Zhao, Yunlu, Guo, Qi, An, Shengjun, Wu, Shuhui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196785/ https://www.ncbi.nlm.nih.gov/pubmed/37215292 http://dx.doi.org/10.1016/j.bbrep.2023.101482

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