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PTEN-induced kinase PINK1 supports colorectal cancer growth by regulating the labile iron pool

Mitophagy is a cargo-specific autophagic process that recycles damaged mitochondria to promote mitochondrial turnover. PTEN-induced putative kinase 1 (PINK1) mediates the canonical mitophagic pathway. However, the role of PINK1 in diseases where mitophagy has been purported to play a role, such as c...

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Detalles Bibliográficos
Autores principales:	Chen, Brandon, Das, Nupur K., Talukder, Indrani, Singhal, Rashi, Castillo, Cristina, Andren, Anthony, Mancias, Joseph D., Lyssiotis, Costas A., Shah, Yatrik M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196865/ https://www.ncbi.nlm.nih.gov/pubmed/37037306 http://dx.doi.org/10.1016/j.jbc.2023.104691

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