Cargando…

Blinding of outcome assessors and its association with outcome in a randomized open-label stroke trial

BACKGROUND: It is challenging for outcome assessors to remain blinded during outcome assessment in trials with prospective randomized open blinded endpoint (PROBE) design. If assessors are able to guess the correct treatment allocation more often than expected based on chance, the assessors may have...

Descripción completa

Detalles Bibliográficos
Autores principales:	van der Ende, Nadinda AM, Roozenbeek, Bob, Broderick, Joseph P, Khatri, Pooja, Lingsma, Hester F, Dippel, Diederik WJ
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196921/ https://www.ncbi.nlm.nih.gov/pubmed/36169032 http://dx.doi.org/10.1177/17474930221131706

Ejemplares similares

Added Value of a Blinded Outcome Adjudication Committee in an Open-Label Randomized Stroke Trial
por: van der Ende, Nadinda A.M., et al.
Publicado: (2021)

Disentangling the Association Between Neurologic Deficits, Patient-Reported Impairments, and Quality of Life After Ischemic Stroke
por: van der Ende, Nadinda A.M., et al.
Publicado: (2023)

Prehospital Triage Strategies for the Transportation of Suspected Stroke Patients in the United States
por: Venema, Esmee, et al.
Publicado: (2020)

National Institutes of Health Stroke Scale: An Alternative Primary Outcome Measure for Trials of Acute Treatment for Ischemic Stroke
por: Chalos, Vicky, et al.
Publicado: (2020)

Type of intracranial hemorrhage after endovascular stroke treatment: association with functional outcome
por: van der Steen, Wouter, et al.
Publicado: (2023)

Outcome Prediction Models for Endovascular Treatment of Ischemic Stroke: Systematic Review and External Validation
por: Kremers, Femke, et al.
Publicado: (2021)

Between-Center Variation in Outcome After Endovascular Treatment of Acute Stroke: Analysis of Two Nationwide Registries
por: Janssen, Paula M., et al.
Publicado: (2022)

Cerebral blood flow quantification with multi-delay arterial spin labeling in ischemic stroke and the association with early neurological outcome
por: Luijten, Sven P.R., et al.
Publicado: (2023)

Determinants of Symptomatic Intracranial Hemorrhage After Endovascular Stroke Treatment: A Retrospective Cohort Study
por: van der Steen, Wouter, et al.
Publicado: (2022)

Symptomatic Intracranial Hemorrhage After Endovascular Stroke Treatment: External Validation of Prediction Models
por: van der Ende, Nadinda A.M., et al.
Publicado: (2023)

Early predictors of functional outcome in poor-grade aneurysmal subarachnoid hemorrhage: a systematic review and meta-analysis
por: de Winkel, Jordi, et al.
Publicado: (2022)

Validity of Early Outcomes as Indicators for Comparing Hospitals on Quality of Stroke Care
por: Amini, Marzyeh, et al.
Publicado: (2023)

Timing of symptomatic intracranial hemorrhage after endovascular stroke treatment
por: van der Steen, Wouter, et al.
Publicado: (2022)

Sensitivity of prehospital stroke scales for different intracranial large vessel occlusion locations
por: Duvekot, Martijne HC, et al.
Publicado: (2021)

Improving quality of stroke care through benchmarking center performance: why focusing on outcomes is not enough
por: Amini, Marzyeh, et al.
Publicado: (2020)

Admission Blood Pressure in Relation to Clinical Outcomes and Successful Reperfusion After Endovascular Stroke Treatment
por: van den Berg, Sophie A., et al.
Publicado: (2020)

Standardized mortality ratios for regionalized acute cardiovascular care
por: den Hartog, Sanne J., et al.
Publicado: (2023)

Effect of first pass reperfusion on outcome in patients with posterior circulation ischemic stroke
por: den Hartog, Sanne J, et al.
Publicado: (2022)

Hospital Variation in Time to Endovascular Treatment for Ischemic Stroke: What Is the Optimal Target for Improvement?
por: den Hartog, Sanne J., et al.
Publicado: (2021)

Personalized Prehospital Triage in Acute Ischemic Stroke: A Decision-Analytic Model
por: Venema, Esmee, et al.
Publicado: (2019)

Prehospital triage of patients with suspected stroke symptoms (PRESTO): protocol of a prospective observational study
por: Venema, Esmee, et al.
Publicado: (2019)

Effect of First‐Pass Reperfusion on Outcome After Endovascular Treatment for Ischemic Stroke
por: den Hartog, Sanne J., et al.
Publicado: (2021)

Utility-Weighted Modified Rankin Scale as Primary Outcome in Stroke Trials: A Simulation Study
por: Dijkland, Simone A., et al.
Publicado: (2018)

Development and validation of the Dutch Stroke Score for predicting disability and functional outcome after ischemic stroke: A tool to support efficient discharge planning
por: de Ridder, Inger R, et al.
Publicado: (2018)

Towards personalised intra-arterial treatment of patients with acute ischaemic stroke: a study protocol for development and validation of a clinical decision aid
por: Mulder, Maxim J H L, et al.
Publicado: (2017)

Prior antiplatelet therapy in patients undergoing endovascular treatment for acute ischemic stroke: Results from the MR CLEAN Registry
por: van de Graaf, Rob A, et al.
Publicado: (2020)

Periprocedural Intravenous Heparin During Endovascular Treatment for Ischemic Stroke: Results From the MR CLEAN Registry
por: van de Graaf, Rob A., et al.
Publicado: (2019)

Selection of patients for intra-arterial treatment for acute ischaemic stroke: development and validation of a clinical decision tool in two randomised trials
por: Venema, Esmee, et al.
Publicado: (2017)

Dual thrombolytic therapy with mutant pro-urokinase and small bolus alteplase for ischemic stroke (DUMAS): study protocol for a multicenter randomized controlled phase II trial
por: van der Ende, Nadinda A. M., et al.
Publicado: (2022)

White Matter Lesions and Outcomes After Endovascular Treatment for Acute Ischemic Stroke: MR CLEAN Registry Results
por: Uniken Venema, Simone M., et al.
Publicado: (2021)

Endovascular versus neurosurgical aneurysm treatment: study protocol for the development and validation of a clinical prediction tool for individualised decision making
por: de Winkel, Jordi, et al.
Publicado: (2022)

Validation of a prediction model for long-term outcome of aphasia after stroke
por: Nouwens, Femke, et al.
Publicado: (2018)

Underpowered trials in critical care medicine: how to deal with them?
por: Roozenbeek, Bob, et al.
Publicado: (2010)

Ordinal outcome analysis improves the detection of between-hospital differences in outcome
por: Ceyisakar, I. E., et al.
Publicado: (2021)

Estimation of treatment effects in observational stroke care data: comparison of statistical approaches
por: Amini, Marzyeh, et al.
Publicado: (2022)

Periprocedural Antithrombotic Treatment During Acute Mechanical Thrombectomy for Ischemic Stroke: A Systematic Review
por: van de Graaf, Rob A., et al.
Publicado: (2018)

Comparison of diffusion weighted imaging b0 with T2*-weighted gradient echo or susceptibility weighted imaging for intracranial hemorrhage detection after reperfusion therapy for ischemic stroke
por: Luijten, Sven P. R., et al.
Publicado: (2023)

Performance feedback on the quality of care in hospitals performing thrombectomy for ischemic stroke (PERFEQTOS): protocol of a stepped wedge cluster randomized trial
por: Amini, Marzyeh, et al.
Publicado: (2021)

Effect of Interhospital Transfer on Endovascular Treatment for Acute Ischemic Stroke
por: Venema, Esmee, et al.
Publicado: (2019)

PRECIOUS: PREvention of Complications to Improve OUtcome in elderly patients with acute Stroke. Rationale and design of a randomised, open, phase III, clinical trial with blinded outcome assessment
por: Reinink, Hendrik, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_39upqnjs6u8n9qef8ipt5p4r4r