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Sarcopenia parameters in active older adults – an eight-year longitudinal study

BACKGROUD: Sarcopenia is a common skeletal muscle syndrome that is common in older adults but can be mitigated by adequate and regular physical activity. The development and severity of sarcopenia is favored by several factors, the most influential of which are a sedentary lifestyle and physical ina...

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Autores principales: Teraž, Kaja, Marusic, Uros, Kalc, Miloš, Šimunič, Boštjan, Pori, Primož, Grassi, Bruno, Lazzer, Stefano, Narici, Marco Vicenzo, Blenkuš, Mojca Gabrijelčič, di Prampero, Pietro Enrico, Reggiani, Carlo, Passaro, Angelina, Biolo, Gianni, Gasparini, Mladen, Pišot, Rado
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197056/
https://www.ncbi.nlm.nih.gov/pubmed/37208654
http://dx.doi.org/10.1186/s12889-023-15734-4
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author Teraž, Kaja
Marusic, Uros
Kalc, Miloš
Šimunič, Boštjan
Pori, Primož
Grassi, Bruno
Lazzer, Stefano
Narici, Marco Vicenzo
Blenkuš, Mojca Gabrijelčič
di Prampero, Pietro Enrico
Reggiani, Carlo
Passaro, Angelina
Biolo, Gianni
Gasparini, Mladen
Pišot, Rado
author_facet Teraž, Kaja
Marusic, Uros
Kalc, Miloš
Šimunič, Boštjan
Pori, Primož
Grassi, Bruno
Lazzer, Stefano
Narici, Marco Vicenzo
Blenkuš, Mojca Gabrijelčič
di Prampero, Pietro Enrico
Reggiani, Carlo
Passaro, Angelina
Biolo, Gianni
Gasparini, Mladen
Pišot, Rado
author_sort Teraž, Kaja
collection PubMed
description BACKGROUD: Sarcopenia is a common skeletal muscle syndrome that is common in older adults but can be mitigated by adequate and regular physical activity. The development and severity of sarcopenia is favored by several factors, the most influential of which are a sedentary lifestyle and physical inactivity. The aim of this observational longitudinal cohort study was to evaluate changes in sarcopenia parameters, based on the EWGSOP2 definition in a population of active older adults after eight years. It was hypothesized that selected active older adults would perform better on sarcopenia tests than the average population. METHODS: The 52 active older adults (22 men and 30 women, mean age: 68.4 ± 5.6 years at the time of their first evaluation) participated in the study at two time points eight-years apart. Three sarcopenia parameters were assessed at both time points: Muscle strength (handgrip test), skeletal muscle mass index, and physical performance (gait speed), these parameters were used to diagnose sarcop0enia according to the EWGSOP2 definition. Additional motor tests were also performed at follow-up measurements to assess participants’ overall fitness. Participants self-reported physical activity and sedentary behavior using General Physical Activity Questionnaire at baseline and at follow-up measurements. RESULTS: In the first measurements we did not detect signs of sarcopenia in any individual, but after 8 years, we detected signs of sarcopenia in 7 participants. After eight years, we detected decline in ; muscle strength (-10.2%; p < .001), muscle mass index (-5.4%; p < .001), and physical performance measured with gait speed (-28.6%; p < .001). Similarly, self-reported physical activity and sedentary behavior declined, too (-25.0%; p = .030 and − 48.5%; p < .001, respectively). CONCLUSIONS: Despite expected lower scores on tests of sarcopenia parameters due to age-related decline, participants performed better on motor tests than reported in similar studies. Nevertheless, the prevalence of sarcopenia was consistent with most of the published literature. TRIAL REGISTRATION: The clinical trial protocol was registered on ClinicalTrials.gov, identifier: NCT04899531. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12889-023-15734-4.
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spelling pubmed-101970562023-05-21 Sarcopenia parameters in active older adults – an eight-year longitudinal study Teraž, Kaja Marusic, Uros Kalc, Miloš Šimunič, Boštjan Pori, Primož Grassi, Bruno Lazzer, Stefano Narici, Marco Vicenzo Blenkuš, Mojca Gabrijelčič di Prampero, Pietro Enrico Reggiani, Carlo Passaro, Angelina Biolo, Gianni Gasparini, Mladen Pišot, Rado BMC Public Health Research BACKGROUD: Sarcopenia is a common skeletal muscle syndrome that is common in older adults but can be mitigated by adequate and regular physical activity. The development and severity of sarcopenia is favored by several factors, the most influential of which are a sedentary lifestyle and physical inactivity. The aim of this observational longitudinal cohort study was to evaluate changes in sarcopenia parameters, based on the EWGSOP2 definition in a population of active older adults after eight years. It was hypothesized that selected active older adults would perform better on sarcopenia tests than the average population. METHODS: The 52 active older adults (22 men and 30 women, mean age: 68.4 ± 5.6 years at the time of their first evaluation) participated in the study at two time points eight-years apart. Three sarcopenia parameters were assessed at both time points: Muscle strength (handgrip test), skeletal muscle mass index, and physical performance (gait speed), these parameters were used to diagnose sarcop0enia according to the EWGSOP2 definition. Additional motor tests were also performed at follow-up measurements to assess participants’ overall fitness. Participants self-reported physical activity and sedentary behavior using General Physical Activity Questionnaire at baseline and at follow-up measurements. RESULTS: In the first measurements we did not detect signs of sarcopenia in any individual, but after 8 years, we detected signs of sarcopenia in 7 participants. After eight years, we detected decline in ; muscle strength (-10.2%; p < .001), muscle mass index (-5.4%; p < .001), and physical performance measured with gait speed (-28.6%; p < .001). Similarly, self-reported physical activity and sedentary behavior declined, too (-25.0%; p = .030 and − 48.5%; p < .001, respectively). CONCLUSIONS: Despite expected lower scores on tests of sarcopenia parameters due to age-related decline, participants performed better on motor tests than reported in similar studies. Nevertheless, the prevalence of sarcopenia was consistent with most of the published literature. TRIAL REGISTRATION: The clinical trial protocol was registered on ClinicalTrials.gov, identifier: NCT04899531. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12889-023-15734-4. BioMed Central 2023-05-19 /pmc/articles/PMC10197056/ /pubmed/37208654 http://dx.doi.org/10.1186/s12889-023-15734-4 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Teraž, Kaja
Marusic, Uros
Kalc, Miloš
Šimunič, Boštjan
Pori, Primož
Grassi, Bruno
Lazzer, Stefano
Narici, Marco Vicenzo
Blenkuš, Mojca Gabrijelčič
di Prampero, Pietro Enrico
Reggiani, Carlo
Passaro, Angelina
Biolo, Gianni
Gasparini, Mladen
Pišot, Rado
Sarcopenia parameters in active older adults – an eight-year longitudinal study
title Sarcopenia parameters in active older adults – an eight-year longitudinal study
title_full Sarcopenia parameters in active older adults – an eight-year longitudinal study
title_fullStr Sarcopenia parameters in active older adults – an eight-year longitudinal study
title_full_unstemmed Sarcopenia parameters in active older adults – an eight-year longitudinal study
title_short Sarcopenia parameters in active older adults – an eight-year longitudinal study
title_sort sarcopenia parameters in active older adults – an eight-year longitudinal study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197056/
https://www.ncbi.nlm.nih.gov/pubmed/37208654
http://dx.doi.org/10.1186/s12889-023-15734-4
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