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Enzymatic comparison of two homologous enzymes reveals N-terminal domain of chondroitinase ABC I regulates substrate selection and product generation

Chondroitinase ABC-type I (CSase ABC I), which can digest both chondroitin sulfate (CS) and dermatan sulfate (DS) in an endolytic manner, is an essential tool in structural and functional studies of CS/DS. Although a few CSase ABC I have been identified from bacteria, the substrate-degrading pattern...

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Detalles Bibliográficos
Autores principales:	Du, Min, Wei, Lin, Yuan, Min, Zou, Ruyi, Xu, Yingying, Wang, Xu, Wang, Wenshuang, Li, Fuchuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197112/ https://www.ncbi.nlm.nih.gov/pubmed/37031818 http://dx.doi.org/10.1016/j.jbc.2023.104692

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