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Semaphorin 4B is an ADAM17-cleaved adipokine that inhibits adipocyte differentiation and thermogenesis
OBJECTIVE: The metalloprotease ADAM17 (also called TACE) plays fundamental roles in homeostasis by shedding key signaling molecules from the cell surface. Although its importance for the immune system and epithelial tissues is well-documented, little is known about the role of ADAM17 in metabolic ho...
Autores principales: | Amin, Abdulbasit, Badenes, Marina, Tüshaus, Johanna, de Carvalho, Érika, Burbridge, Emma, Faísca, Pedro, Trávníčková, Květa, Barros, André, Carobbio, Stefania, Domingos, Pedro M., Vidal-Puig, Antonio, Moita, Luís F., Maguire, Sarah, Stříšovský, Kvido, Ortega, Francisco J., Fernández-Real, José Manuel, Lichtenthaler, Stefan F., Adrain, Colin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197113/ https://www.ncbi.nlm.nih.gov/pubmed/37121509 http://dx.doi.org/10.1016/j.molmet.2023.101731 |
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