Synthesis, Computational Insights, and Evaluation of Novel Sigma Receptors Ligands

[Image: see text] The development of diazabicyclo[4.3.0]nonane and 2,7-diazaspiro[3.5]nonane derivatives as sigma receptors (SRs) ligands is reported. The compounds were evaluated in S1R and S2R binding assays, and modeling studies were carried out to analyze the binding mode. The most notable compo...

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Detalles Bibliográficos
Autores principales: Dichiara, Maria, Ambrosio, Francesca Alessandra, Barbaraci, Carla, González-Cano, Rafael, Costa, Giosuè, Parenti, Carmela, Marrazzo, Agostino, Pasquinucci, Lorella, Cobos, Enrique J., Alcaro, Stefano, Amata, Emanuele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197133/
https://www.ncbi.nlm.nih.gov/pubmed/37155827
http://dx.doi.org/10.1021/acschemneuro.3c00074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197133/
https://www.ncbi.nlm.nih.gov/pubmed/37155827
http://dx.doi.org/10.1021/acschemneuro.3c00074

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