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Loss of AMPKα2 promotes melanoma tumor growth and brain metastasis

AMP-activated protein kinase (AMPK) is a critical cellular energy sensor at the interface of metabolism and cancer. However, the role of AMPK in carcinogenesis remains unclear. Here, through analysis of the TCGA melanoma dataset, we found that PRKAA2 gene that encodes the α2 subunit of AMPK is mutat...

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Detalles Bibliográficos
Autores principales:	Yuan, Ping, Teng, Da, de Groot, Evelyn, Li, Man, Trousil, Sebastian, Shen, Che-Hung, Roszik, Jason, Davies, Michael A., Gopal, Y.N. Vashisht, Zheng, Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197146/ https://www.ncbi.nlm.nih.gov/pubmed/37213225 http://dx.doi.org/10.1016/j.isci.2023.106791

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