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Development of high affinity broadly reactive aptamers for spike protein of multiple SARS-CoV-2 variants

We have developed broadly reactive aptamers against multiple variants by alternating the target between spike proteins from different SARS-CoV-2 variants during the selection process. In this process we have developed aptamers which can recognise all variants, from the original wild-type ‘Wuhan’ str...

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Detalles Bibliográficos
Autores principales:	Le, Thao T., Benton, Donald J., Wrobel, Antoni G., Gamblin, Steven J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2023
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197177/ https://www.ncbi.nlm.nih.gov/pubmed/37213341 http://dx.doi.org/10.1039/d3ra01382k

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