Cargando…

Internal quality control – past, present and future trends

OBJECTIVES: This paper offers an historical view, through a summary of the internal quality control (IQC) models used from second half of twentyth century to those performed today and wants to give a projection on how the future should be addressed. METHODS: The material used in this work study are...

Descripción completa

Detalles Bibliográficos
Autores principales: Ricós, Carmen, Fernandez-Calle, Pilar, Perich, Carmen, Westgard, James O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197334/
https://www.ncbi.nlm.nih.gov/pubmed/37362142
http://dx.doi.org/10.1515/almed-2022-0029
_version_ 1785044530032017408
author Ricós, Carmen
Fernandez-Calle, Pilar
Perich, Carmen
Westgard, James O.
author_facet Ricós, Carmen
Fernandez-Calle, Pilar
Perich, Carmen
Westgard, James O.
author_sort Ricós, Carmen
collection PubMed
description OBJECTIVES: This paper offers an historical view, through a summary of the internal quality control (IQC) models used from second half of twentyth century to those performed today and wants to give a projection on how the future should be addressed. METHODS: The material used in this work study are all papers collected referring IQC procedures. The method used is the critical analysis of the different IQC models with a discussion on the weak and the strong points of each model. RESULTS: First models were based on testing control materials and using multiples of the analytical procedure standard deviation as control limits. Later, these limits were substituted by values related with the intended use of test, mainly derived from biological variation. For measurands with no available control material methods based on replicate analysis of patient’ samples were developed and have been improved recently; also, the sigma metrics that relates the quality desired with the laboratory performance has resulted in a highly efficient quality control model. Present tendency is to modulate IQC considering the workload and the impact of analytical failure in the patent harm. CONCLUSIONS: This paper remarks the strong points of IQC models, indicates the weak points that should be eliminated from practice and gives a future projection on how to promote patient safety through laboratory examinations.
format Online
Article
Text
id pubmed-10197334
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher De Gruyter
record_format MEDLINE/PubMed
spelling pubmed-101973342023-06-23 Internal quality control – past, present and future trends Ricós, Carmen Fernandez-Calle, Pilar Perich, Carmen Westgard, James O. Adv Lab Med Article OBJECTIVES: This paper offers an historical view, through a summary of the internal quality control (IQC) models used from second half of twentyth century to those performed today and wants to give a projection on how the future should be addressed. METHODS: The material used in this work study are all papers collected referring IQC procedures. The method used is the critical analysis of the different IQC models with a discussion on the weak and the strong points of each model. RESULTS: First models were based on testing control materials and using multiples of the analytical procedure standard deviation as control limits. Later, these limits were substituted by values related with the intended use of test, mainly derived from biological variation. For measurands with no available control material methods based on replicate analysis of patient’ samples were developed and have been improved recently; also, the sigma metrics that relates the quality desired with the laboratory performance has resulted in a highly efficient quality control model. Present tendency is to modulate IQC considering the workload and the impact of analytical failure in the patent harm. CONCLUSIONS: This paper remarks the strong points of IQC models, indicates the weak points that should be eliminated from practice and gives a future projection on how to promote patient safety through laboratory examinations. De Gruyter 2022-05-23 /pmc/articles/PMC10197334/ /pubmed/37362142 http://dx.doi.org/10.1515/almed-2022-0029 Text en © 2022 the author(s), published by De Gruyter, Berlin/Boston https://creativecommons.org/licenses/by/4.0/This work is licensed under the Creative Commons Attribution 4.0 International License.
spellingShingle Article
Ricós, Carmen
Fernandez-Calle, Pilar
Perich, Carmen
Westgard, James O.
Internal quality control – past, present and future trends
title Internal quality control – past, present and future trends
title_full Internal quality control – past, present and future trends
title_fullStr Internal quality control – past, present and future trends
title_full_unstemmed Internal quality control – past, present and future trends
title_short Internal quality control – past, present and future trends
title_sort internal quality control – past, present and future trends
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197334/
https://www.ncbi.nlm.nih.gov/pubmed/37362142
http://dx.doi.org/10.1515/almed-2022-0029
work_keys_str_mv AT ricoscarmen internalqualitycontrolpastpresentandfuturetrends
AT fernandezcallepilar internalqualitycontrolpastpresentandfuturetrends
AT perichcarmen internalqualitycontrolpastpresentandfuturetrends
AT westgardjameso internalqualitycontrolpastpresentandfuturetrends