Intestinal endothelial cells increase HIV infection and latency in resting and activated CD4 + T cells, particularly affecting CCR6 + CD4 + T cells

BACKGROUND: With suppressive antiretroviral therapy, HIV infection is well-managed in most patients. However, eradication and cure are still beyond reach due to latent viral reservoirs in CD4 + T cells, particularly in lymphoid tissue environments including the gut associated lymphatic tissues. In H...

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Detalles Bibliográficos
Autores principales: Eddy, Jessica, Pham, Fisher, Chee, Rachel, Park, Esther, Dapprich, Nathan, DeRuiter, Stacy L., Shen, Anding
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197447/
https://www.ncbi.nlm.nih.gov/pubmed/37202790
http://dx.doi.org/10.1186/s12977-023-00621-y

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