Premature ovarian insufficiency is associated with global alterations in the regulatory landscape and gene expression in balanced X-autosome translocations

BACKGROUND: Patients with balanced X-autosome translocations and premature ovarian insufficiency (POI) constitute an interesting paradigm to study the effect of chromosome repositioning. Their breakpoints are clustered within cytobands Xq13–Xq21, 80% of them in Xq21, and usually, no gene disruption...

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Detalles Bibliográficos
Autores principales: Di-Battista, Adriana, Favilla, Bianca Pereira, Zamariolli, Malú, Nunes, Natália, Defelicibus, Alexandre, Armelin-Correa, Lucia, da Silva, Israel Tojal, Reymond, Alexandre, Moyses-Oliveira, Mariana, Melaragno, Maria Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197467/
https://www.ncbi.nlm.nih.gov/pubmed/37202802
http://dx.doi.org/10.1186/s13072-023-00493-8

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