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Succinylation of a KEAP1 sensor lysine promotes NRF2 activation

Crosstalk between metabolism and stress-responsive signaling is essential to maintaining cellular homeostasis. One way this crosstalk is achieved is through the covalent modification of proteins by endogenous, reactive metabolites that regulate the activity of key stress-responsive transcription fac...

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Detalles Bibliográficos
Autores principales:	Ibrahim, Lara, Stanton, Caroline, Nutsch, Kayla, Nguyen, Thu, Li-Ma, Chloris, Ko, Yeonjin, Lander, Gabriel C., Wiseman, R. Luke, Bollong, Michael J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197519/ https://www.ncbi.nlm.nih.gov/pubmed/37215033 http://dx.doi.org/10.1101/2023.05.08.539908

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