HIV-1 Vpu protein forms stable oligomers in aqueous solution via its transmembrane domain self-association

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We report our findings on the assembly of the HIV-1 protein Vpu into soluble oligomers. Vpu is a key to HIV-1 protein. It has been considered exclusively a single-pass membrane protein. However, we revealed that this protein forms stable oligomers in aqueous solution, which is an interesting and rat...

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Detalles Bibliográficos
Autores principales: Majeed, Saman, Dang, Lan, Islam, Md Majharul, Ishola, Olamide, Borbat, Peter P., Ludtke, Steven J., Georgieva, Elka R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197565/
https://www.ncbi.nlm.nih.gov/pubmed/37214796
http://dx.doi.org/10.1101/2023.05.08.539839
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