Simultaneous enhancement of multiple functional properties using evolution-informed protein design

Designing optimized proteins is important for a range of practical applications. Protein design is a rapidly developing field that would benefit from approaches that enable many changes in the amino acid primary sequence, rather than a small number of mutations, while maintaining structure and enhan...

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Detalles Bibliográficos
Autores principales: Fram, Benjamin, Truebridge, Ian, Su, Yang, Riesselman, Adam J., Ingraham, John B., Passera, Alessandro, Napier, Eve, Thadani, Nicole N., Lim, Samuel, Roberts, Kristen, Kaur, Gurleen, Stiffler, Michael, Marks, Debora S., Bahl, Christopher D., Khan, Amir R., Sander, Chris, Gauthier, Nicholas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197589/
https://www.ncbi.nlm.nih.gov/pubmed/37214973
http://dx.doi.org/10.1101/2023.05.09.539914

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197589/
https://www.ncbi.nlm.nih.gov/pubmed/37214973
http://dx.doi.org/10.1101/2023.05.09.539914

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