RNA polymerase II pausing is essential during spermatogenesis for appropriate gene expression and completion of meiosis

Male germ cell development requires precise regulation of gene activity in a cell-type and stage-specific manner, with perturbations in gene expression during spermatogenesis associated with infertility. Here, we use steady-state, nascent and single-cell RNA sequencing strategies to comprehensively...

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Detalles Bibliográficos
Autores principales: Kaye, Emily G., Nelson, Geoffrey M., Zomer, Helena D., Roy, Debarun, Joseph, Irene Infancy, Adelman, Karen, Reddi, Prabhakara P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197597/
https://www.ncbi.nlm.nih.gov/pubmed/37215034
http://dx.doi.org/10.1101/2023.05.08.539879

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