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SARS-COV-2 Spike Protein Fragment eases Amyloidogenesis of α-Synuclein

Parkinson’s Disease is accompanied by presence of amyloids in the brain formed of α-synuclein chains. Correlation between COVID-19 and the onset of Parkinson’s disease let to the idea that amyloidogenic segments in SARS-COV-2 proteins can induce aggregation of α-synuclein. Using molecular dynamic si...

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Detalles Bibliográficos
Autores principales: Chesney, Andrew D., Maiti, Buddhadev, Hansmann, Ulrich H. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197603/
https://www.ncbi.nlm.nih.gov/pubmed/37214999
http://dx.doi.org/10.1101/2023.05.06.539715