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Within-host rhinovirus evolution in upper and lower respiratory tract highlights capsid variability and mutation-independent compartmentalization

BACKGROUND: Human rhinovirus (HRV) infections can progress from the upper (URT) to lower (LRT) respiratory tract in immunocompromised individuals, causing high rates of fatal pneumonia. Little is known about how HRV evolves within hosts during infection. METHODS: We sequenced HRV complete genomes fr...

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Detalles Bibliográficos
Autores principales:	Makhsous, Negar, Goya, Stephanie, Avendaño, Carlos, Rupp, Jason, Kuypers, Jane, Jerome, Keith R., Boeckh, Michael, Waghmare, Alpana, Greninger, Alexander L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197658/ https://www.ncbi.nlm.nih.gov/pubmed/37214809 http://dx.doi.org/10.1101/2023.05.11.540440

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