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The Upstream Sequence Transcription Complex Dictates Nucleosome Positioning and Promoter Accessibility at piRNA Genes in the C. elegans Germ Line

The piRNA pathway is a conserved germline-specific small RNA pathway that ensures genomic integrity and continued fertility. In C. elegans and other nematodes, Type-I piRNA precursor transcripts are expressed from over 10,000 small, independently regulated genes clustered within two discrete domains...

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Detalles Bibliográficos
Autores principales: Sanchez, Nancy, Gonzalez, Lauren E, Reinke, Valerie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197682/
https://www.ncbi.nlm.nih.gov/pubmed/37215016
http://dx.doi.org/10.1101/2023.05.10.540274

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