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Discovery and Validation of Context-Dependent Synthetic Mammalian Promoters

Cellular transcription enables cells to adapt to various stimuli and maintain homeostasis. Transcription factors bind to transcription response elements (TREs) in gene promoters, initiating transcription. Synthetic promoters, derived from natural TREs, can be engineered to control exogenous gene exp...

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Detalles Bibliográficos
Autores principales:	Zahm, Adam M., Owens, William S., Himes, Samuel R., Rondem, Kathleen E., Fallon, Braden S., Gormick, Alexa N., Bloom, Joshua S., Kosuri, Sriram, Chan, Henry, English, Justin G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197685/ https://www.ncbi.nlm.nih.gov/pubmed/37214829 http://dx.doi.org/10.1101/2023.05.11.539703

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