Cargando…

17 β-estradiol impedes aortic root dilation and rupture in male Marfan mice

Marfan syndrome causes a hereditary form of thoracic aortic aneurysms with dilation of the aortic root. Human and animal models suggest a worse phenotype for males compared to females with respect to aneurysm size and risk of dissection. In this study we examine the effects of 17 β-estradiol on aort...

Descripción completa

Detalles Bibliográficos
Autores principales: Saddic, Louis, Escopete, Sean, Zilberberg, Lior, Kalsow, Shannon, Gupta, Divya, Egbhali, Mansoureh, Parker, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197695/
https://www.ncbi.nlm.nih.gov/pubmed/37215011
http://dx.doi.org/10.1101/2023.05.09.540071