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17 β-estradiol impedes aortic root dilation and rupture in male Marfan mice

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Marfan syndrome causes a hereditary form of thoracic aortic aneurysms with dilation of the aortic root. Human and animal models suggest a worse phenotype for males compared to females with respect to aneurysm size and risk of dissection. In this study we examine the effects of 17 β-estradiol on aort...

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Detalles Bibliográficos
Autores principales:	Saddic, Louis, Escopete, Sean, Zilberberg, Lior, Kalsow, Shannon, Gupta, Divya, Egbhali, Mansoureh, Parker, Sarah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197695/ https://www.ncbi.nlm.nih.gov/pubmed/37215011 http://dx.doi.org/10.1101/2023.05.09.540071

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