Cardiomyocyte Targeting Peptide to Deliver Amiodarone

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BACKGROUND: Amiodarone is underutilized due to significant off-target toxicities. We hypothesized that targeted delivery to the heart would lead to lowering of dose by utilizing a cardiomyocyte targeting peptide (CTP), a cell penetrating peptide identified by our prior phage display work. METHODS: C...

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Detalles Bibliográficos
Autores principales: Zahid, Maliha, Weber, Beth, Yurko, Ray, Islam, Kazi, Agrawal, Vaishavi, Lopuszynski, Jack, Yagi, Hisato, Salama, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197706/
https://www.ncbi.nlm.nih.gov/pubmed/37214919
http://dx.doi.org/10.1101/2023.05.10.540206

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