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Development and Application of Pharmacological Statin-Associated Muscle Symptoms Phenotyping Algorithms Using Structured and Unstructured Electronic Health Records Data

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BACKGROUND: Statins are widely prescribed cholesterol-lowering medications in the US, but their clinical benefits can be diminished by statin-associated muscle symptoms (SAMS), leading to discontinuation. In this study, we aimed to develop and validate a pharmacological SAMS clinical phenotyping alg...

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Detalles Bibliográficos
Autores principales:	Sun, Boguang, Yew, Pui Ying, Chi, Chih-Lin, Song, Meijia, Loth, Matt, Zhang, Rui, Straka, Robert J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197715/ https://www.ncbi.nlm.nih.gov/pubmed/37215024 http://dx.doi.org/10.1101/2023.05.04.23289523

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