Development and Application of Pharmacological Statin-Associated Muscle Symptoms Phenotyping Algorithms Using Structured and Unstructured Electronic Health Records Data

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BACKGROUND: Statins are widely prescribed cholesterol-lowering medications in the US, but their clinical benefits can be diminished by statin-associated muscle symptoms (SAMS), leading to discontinuation. In this study, we aimed to develop and validate a pharmacological SAMS clinical phenotyping alg...

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Detalles Bibliográficos
Autores principales: Sun, Boguang, Yew, Pui Ying, Chi, Chih-Lin, Song, Meijia, Loth, Matt, Zhang, Rui, Straka, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197715/
https://www.ncbi.nlm.nih.gov/pubmed/37215024
http://dx.doi.org/10.1101/2023.05.04.23289523
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