Cargando…

Inferring Alzheimer’s disease pathologic traits from clinical measures in living adults

BACKGROUND AND OBJECTIVES: Develop imputation models using clinical measures to infer Alzheimer’s disease neuropathologic changes (AD-NC) in living adults to identify adults at risk for Alzheimer’s disease (AD). METHODS: We used clinical and postmortem data of two prospective cohort studies –– Memor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Jingjing, Liu, Xizhu, Oveisgharan, Shahram, Zammit, Andrea R., Nag, Sukriti, Bennett, David A, Buchman, Aron S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197717/ https://www.ncbi.nlm.nih.gov/pubmed/37214885 http://dx.doi.org/10.1101/2023.05.08.23289668

Ejemplares similares

Incident mobility disability, parkinsonism, and mortality in community-dwelling older adults
por: Oveisgharan, Shahram, et al.
Publicado: (2021)

Total daily physical activity, brain pathologies, and parkinsonism in older adults
por: Oveisgharan, Shahram, et al.
Publicado: (2020)

Correlates of Person-Specific Rates of Change in Sensor-Derived Physical Activity Metrics of Daily Living in the Rush Memory and Aging Project
por: Buchman, Aron S., et al.
Publicado: (2023)

Volumetric brain correlates of gait associated with cognitive decline in community-dwelling older adults
por: Poole, Victoria N., et al.
Publicado: (2023)

TDP-43 pathology in anterior temporal pole cortex in aging and Alzheimer’s disease
por: Nag, Sukriti, et al.
Publicado: (2018)

Cortical proteins may provide motor resilience in older adults
por: Buchman, Aron S., et al.
Publicado: (2021)

Relationship between objectively measured physical activity on neuropathology and cognitive outcomes in older adults: Resistance versus resilience?
por: Memel, Molly, et al.
Publicado: (2021)

Cortical Proteins and Individual Differences in Cognitive Resilience in Older Adults
por: Zammit, Andrea R., et al.
Publicado: (2022)

Novel Variance-Component TWAS method for studying complex human diseases with applications to Alzheimer’s dementia
por: Tang, Shizhen, et al.
Publicado: (2021)

A scalable Bayesian functional GWAS method accounting for multivariate quantitative functional annotations with applications for studying Alzheimer disease
por: Chen, Junyu, et al.
Publicado: (2022)

The Measurement of Adult Pathological Demand Avoidance Traits
por: Egan, Vincent, et al.
Publicado: (2018)

Post-mortem brain pathology is related to declining respiratory function in community-dwelling older adults
por: Buchman, Aron S., et al.
Publicado: (2015)

A Clinicopathological Report of a 93-Year-Old Former Street Boxer With Coexistence of Chronic Traumatic Encephalopathy, Alzheimer's Disease, Dementia With Lewy Bodies, and Hippocampal Sclerosis With TDP-43 Pathology
por: Yang, Chunhui, et al.
Publicado: (2020)

Differential gene expression analysis based on linear mixed model corrects false positive inflation for studying quantitative traits
por: Tang, Shizhen, et al.
Publicado: (2023)

Genetic risk for Alzheimer’s dementia predicts motor deficits through multi-omic systems in older adults
por: Tasaki, Shinya, et al.
Publicado: (2019)

Sleep fragmentation, microglial aging, and cognitive impairment in adults with and without Alzheimer’s dementia
por: Kaneshwaran, Kirusanthy, et al.
Publicado: (2019)

Seasonal plasticity of cognition and related biological measures in adults with and without Alzheimer disease: Analysis of multiple cohorts
por: Lim, Andrew S. P., et al.
Publicado: (2018)

Circadian disturbances in Alzheimer’s disease progression: a prospective observational cohort study of community-based older adults
por: Li, Peng, et al.
Publicado: (2020)

The association of Lewy bodies with limbic-predominant age-related TDP-43 encephalopathy neuropathologic changes and their role in cognition and Alzheimer’s dementia in older persons
por: Agrawal, Sonal, et al.
Publicado: (2021)

Poor Decision Making Is a Consequence of Cognitive Decline among Older Persons without Alzheimer’s Disease or Mild Cognitive Impairment
por: Boyle, Patricia A., et al.
Publicado: (2012)

Mixed Neuropathologies, Neural Motor Resilience and Target Discovery for Therapies of Late-Life Motor Impairment
por: Buchman, Aron S., et al.
Publicado: (2022)

Isolated spinal neurosarcoidosis: An enigmatic intramedullary spinal cord pathology-case report and review of the literature
por: Kasliwal, Manish K., et al.
Publicado: (2013)

Non-invasive Brain Stimulation and Prism Adaptation in Art Constructive Errors in Painting
por: Vatanparasti, Shole, et al.
Publicado: (2023)

Brain Magnetic Susceptibility is Associated With Slower Gait in Community-Dwelling Older Adults
por: Poole, Victoria, et al.
Publicado: (2021)

Limbic‐predominant age‐related TDP‐43 encephalopathy neuropathologic change and microvascular pathologies in community‐dwelling older persons
por: Agrawal, Sonal, et al.
Publicado: (2021)

Using a Body-Fixed Sensor to Identify Subclinical Gait Difficulties in Older Adults with IADL Disability: Maximizing the Output of the Timed Up and Go
por: Weiss, Aner, et al.
Publicado: (2013)

Systemic brain derived neurotrophic factor but not intestinal barrier integrity is associated with cognitive decline and incident Alzheimer’s disease
por: Voigt, Robin M., et al.
Publicado: (2021)

Fractal regulation and incident Alzheimer’s disease in elderly individuals
por: Li, Peng, et al.
Publicado: (2018)

Diverse Motor Performances Are Related to Incident Cognitive Impairment in Community-Dwelling Older Adults
por: Beeri, Michal Schnaider, et al.
Publicado: (2021)

Association of Heel Bone Mineral Density With Incident Disability and Mortality in Community‐Dwelling Older Adults
por: Ross, Ryan D, et al.
Publicado: (2020)

No increased circular inference in adults with high levels of autistic traits or autism
por: Angeletos Chrysaitis, Nikitas, et al.
Publicado: (2021)

Face-to-trait inferences in Japanese children and adults based on Caucasian faces
por: Sakuta, Yuiko
Publicado: (2022)

A Case Report of Homocystinuria With Dystonia and Stroke
por: Rezazadeh, Arezoo, et al.
Publicado: (2014)

Complications of therapeutic plasma exchange in patients with neurological disorders
por: Afzali, Mahdieh, et al.
Publicado: (2020)

The use of brain stimulation in the rehabilitation of walking disability in patients with multiple sclerosis: A randomized double-blind clinical trial study
por: Oveisgharan, Shahram, et al.
Publicado: (2019)

Higher Dietary Intake of Advanced Glycation End Products Is Associated with Faster Cognitive Decline in Community-Dwelling Older Adults
por: Schnaider Beeri, Michal, et al.
Publicado: (2022)

Harm avoidance is associated with progression of parkinsonism in community-dwelling older adults: a prospective cohort study
por: Buchman, Aron S, et al.
Publicado: (2014)

Associations between Quantitative Mobility Measures Derived from Components of Conventional Mobility Testing and Parkinsonian Gait in Older Adults
por: Buchman, Aron S., et al.
Publicado: (2014)

Gait Detection from a Wrist-Worn Sensor Using Machine Learning Methods: A Daily Living Study in Older Adults and People with Parkinson’s Disease
por: Brand, Yonatan E., et al.
Publicado: (2022)

Case fatality rate ‎and disability of stroke in Isfahan, Iran: Isfahan stroke registry
por: Oveisgharan, Shahram, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_2idp6hts131a1rvd42rb5fvtol