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Clinical utility of liquid biopsy for the diagnosis and monitoring of EML4-ALK NSCLC patients

BACKGROUND: Genomic rearrangement in anaplastic lymphoma kinase (ALK) gene occurs in 3−7% of patients with non-small-cell lung cancer (NSCLC). The detection of this alteration is crucial as ALK positive NSCLC patients benefit from ALK inhibitors, which improve both the patient's quality of life...

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Detalles Bibliográficos
Autores principales: Sánchez-Herrero, Estela, Provencio, Mariano, Romero, Atocha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197761/
https://www.ncbi.nlm.nih.gov/pubmed/37362555
http://dx.doi.org/10.1515/almed-2019-0019