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Vitamin D deficiency increases vulnerability to canagliflozin-induced adverse effects on 1,25-dihydroxyvitamin D and PTH

CONTEXT. Canagliflozin has been reported to increase the risk of bone fracture – possibly mediated by decreasing 1,25-dihydroxyvitamin D [1,25(OH)(2)D] and increasing PTH. OBJECTIVE. To investigate whether baseline vitamin D (VitD) deficiency renders individuals vulnerable to this adverse effect and...

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Detalles Bibliográficos
Autores principales:	Yazdi, Zhinous Shahidzadeh, Streeten, Elizabeth A., Whitlatch, Hilary B., Montasser, May E., Beitelshees, Amber L., Taylor, Simeon I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197796/ https://www.ncbi.nlm.nih.gov/pubmed/37214882 http://dx.doi.org/10.1101/2023.05.11.23289854

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