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A digital health intervention to support patients with chronic pain during prescription opioid tapering: a pilot randomised controlled trial

INTRODUCTION: Recent changes in opioid prescribing guidelines have led to an increasing number of patients with chronic pain being recommended to taper. However, opioid tapering can be challenging, and many patients require support. OBJECTIVES: We evaluated the feasibility, acceptability, and potent...

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Autores principales: Gholamrezaei, Ali, Magee, Michael R, McNeilage, Amy G, Dwyer, Leah, Sim, Alison, Ferreira, Manuela L, Darnall, Beth D, Brake, Timothy, Aggarwal, Arun, Craigie, Meredith, Hollington, Irina, Glare, Paul, Ashton-James, Claire E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197816/
https://www.ncbi.nlm.nih.gov/pubmed/37214982
http://dx.doi.org/10.1101/2023.05.10.23289771
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author Gholamrezaei, Ali
Magee, Michael R
McNeilage, Amy G
Dwyer, Leah
Sim, Alison
Ferreira, Manuela L
Darnall, Beth D
Brake, Timothy
Aggarwal, Arun
Craigie, Meredith
Hollington, Irina
Glare, Paul
Ashton-James, Claire E
author_facet Gholamrezaei, Ali
Magee, Michael R
McNeilage, Amy G
Dwyer, Leah
Sim, Alison
Ferreira, Manuela L
Darnall, Beth D
Brake, Timothy
Aggarwal, Arun
Craigie, Meredith
Hollington, Irina
Glare, Paul
Ashton-James, Claire E
author_sort Gholamrezaei, Ali
collection PubMed
description INTRODUCTION: Recent changes in opioid prescribing guidelines have led to an increasing number of patients with chronic pain being recommended to taper. However, opioid tapering can be challenging, and many patients require support. OBJECTIVES: We evaluated the feasibility, acceptability, and potential efficacy of a co-designed psycho-educational video and SMS text messaging intervention to support patients with chronic pain during prescription opioid tapering. METHODS: A pilot randomised controlled trial was conducted. In addition to their usual care, participants in the intervention group received a psycho-educational video and 28 days of text messages (two SMS/day). The control group received usual care. The feasibility, acceptability, and potential efficacy of the intervention were evaluated. The primary outcome was opioid tapering self-efficacy. Secondary outcomes were pain intensity and interference, anxiety and depression symptom severity, pain catastrophising, and pain self-efficacy. RESULTS: Of 28 randomised participants, 26 completed the study (13 in each group). Text message delivery was 99.2% successful. Most participants rated the messages as useful, supportive, encouraging, and engaging, 78.5% would recommend the intervention to others, and 64% desired a longer intervention period. Tapering self-efficacy (Cohen’s d = 0.74) and pain self-efficacy (d = 0.41) were higher and pain intensity (d = 0.65) and affective interference (d = 0.45) lower in the intervention group at week 4. CONCLUSIONS: It is feasible, acceptable, and potentially efficacious to support patients with chronic pain during prescription opioid tapering with a psycho-educational video and SMS text messaging intervention. A definitive trial has been initiated to test a 12-week intervention.
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spelling pubmed-101978162023-05-20 A digital health intervention to support patients with chronic pain during prescription opioid tapering: a pilot randomised controlled trial Gholamrezaei, Ali Magee, Michael R McNeilage, Amy G Dwyer, Leah Sim, Alison Ferreira, Manuela L Darnall, Beth D Brake, Timothy Aggarwal, Arun Craigie, Meredith Hollington, Irina Glare, Paul Ashton-James, Claire E medRxiv Article INTRODUCTION: Recent changes in opioid prescribing guidelines have led to an increasing number of patients with chronic pain being recommended to taper. However, opioid tapering can be challenging, and many patients require support. OBJECTIVES: We evaluated the feasibility, acceptability, and potential efficacy of a co-designed psycho-educational video and SMS text messaging intervention to support patients with chronic pain during prescription opioid tapering. METHODS: A pilot randomised controlled trial was conducted. In addition to their usual care, participants in the intervention group received a psycho-educational video and 28 days of text messages (two SMS/day). The control group received usual care. The feasibility, acceptability, and potential efficacy of the intervention were evaluated. The primary outcome was opioid tapering self-efficacy. Secondary outcomes were pain intensity and interference, anxiety and depression symptom severity, pain catastrophising, and pain self-efficacy. RESULTS: Of 28 randomised participants, 26 completed the study (13 in each group). Text message delivery was 99.2% successful. Most participants rated the messages as useful, supportive, encouraging, and engaging, 78.5% would recommend the intervention to others, and 64% desired a longer intervention period. Tapering self-efficacy (Cohen’s d = 0.74) and pain self-efficacy (d = 0.41) were higher and pain intensity (d = 0.65) and affective interference (d = 0.45) lower in the intervention group at week 4. CONCLUSIONS: It is feasible, acceptable, and potentially efficacious to support patients with chronic pain during prescription opioid tapering with a psycho-educational video and SMS text messaging intervention. A definitive trial has been initiated to test a 12-week intervention. Cold Spring Harbor Laboratory 2023-05-11 /pmc/articles/PMC10197816/ /pubmed/37214982 http://dx.doi.org/10.1101/2023.05.10.23289771 Text en https://creativecommons.org/licenses/by-nc/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License (https://creativecommons.org/licenses/by-nc/4.0/) , which allows reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
spellingShingle Article
Gholamrezaei, Ali
Magee, Michael R
McNeilage, Amy G
Dwyer, Leah
Sim, Alison
Ferreira, Manuela L
Darnall, Beth D
Brake, Timothy
Aggarwal, Arun
Craigie, Meredith
Hollington, Irina
Glare, Paul
Ashton-James, Claire E
A digital health intervention to support patients with chronic pain during prescription opioid tapering: a pilot randomised controlled trial
title A digital health intervention to support patients with chronic pain during prescription opioid tapering: a pilot randomised controlled trial
title_full A digital health intervention to support patients with chronic pain during prescription opioid tapering: a pilot randomised controlled trial
title_fullStr A digital health intervention to support patients with chronic pain during prescription opioid tapering: a pilot randomised controlled trial
title_full_unstemmed A digital health intervention to support patients with chronic pain during prescription opioid tapering: a pilot randomised controlled trial
title_short A digital health intervention to support patients with chronic pain during prescription opioid tapering: a pilot randomised controlled trial
title_sort digital health intervention to support patients with chronic pain during prescription opioid tapering: a pilot randomised controlled trial
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197816/
https://www.ncbi.nlm.nih.gov/pubmed/37214982
http://dx.doi.org/10.1101/2023.05.10.23289771
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