IFNα induces CCR5 in CD4(+) T-cells, causing its anti- HIV inefficiency and its subsequent pathogenic elevation, partially controlled by anti-HIV therapy

Like EC, we find that ART-treated patients control serum IFNα concentration and show few immune cell alterations enabling a healthy but fragile medical status. However, treatment interruption leads to elevated IFNα reflecting virus production indicating that like EC, ART does not achieve a virologic...

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Detalles Bibliográficos
Autores principales: Le Buanec, Hélène, Schiavon, Valérie, Merandet, Marine, How-Kit, Alexandre, Song, Hongshuo, Bergerat, David, Fombellida-Lopez, Céline, Bensussan, Armand, Bouaziz, Jean-David, Burny, Arsène, Darcis, Gilles, Sajadi, Mohammad M., Kottilil, Shyamasundaran, Zagury, Daniel, Gallo, Robert C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197818/
https://www.ncbi.nlm.nih.gov/pubmed/37214795
http://dx.doi.org/10.21203/rs.3.rs-2813616/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197818/
https://www.ncbi.nlm.nih.gov/pubmed/37214795
http://dx.doi.org/10.21203/rs.3.rs-2813616/v1

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