Cargando…
Role of Exosomes in the Invasion and Metastasis of Ovarian Cancer and Application Potential of Clinical Diagnosis and Treatment
Ovarian cancer is a highly lethal form of cancer in females, largely due to extensive metastases that often accompany the initial diagnosis. Exosomes are microvesicles size from 30 to 100nm, which can be secreted by most cells. These special extracellular vesicles play a vital role in the metastasis...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197940/ https://www.ncbi.nlm.nih.gov/pubmed/37215442 http://dx.doi.org/10.7150/jca.83663 |
_version_ | 1785044646648348672 |
---|---|
author | Zhu, Yifei Wang, Cheng Ma, Ziyu Li, Feifei Xu, Chunwei Pan, Weiwei Liu, Aijun |
author_facet | Zhu, Yifei Wang, Cheng Ma, Ziyu Li, Feifei Xu, Chunwei Pan, Weiwei Liu, Aijun |
author_sort | Zhu, Yifei |
collection | PubMed |
description | Ovarian cancer is a highly lethal form of cancer in females, largely due to extensive metastases that often accompany the initial diagnosis. Exosomes are microvesicles size from 30 to 100nm, which can be secreted by most cells. These special extracellular vesicles play a vital role in the metastasis of ovarian cancer. In this study, we conducted a comprehensive review of current research pertaining to the role of exosomes in ovarian cancer, utilizing the PubMed(®) and Web of Science databases. Our review highlights the progress in elucidating the mechanisms by which exosomes facilitate ovarian cancer progression. Additionally, we discuss the potential of exosomes as a novel therapeutic target for ovarian cancer treatment. Overall, our review provides valuable insights into the current state of research on exosomes in ovarian cancer therapy. |
format | Online Article Text |
id | pubmed-10197940 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Ivyspring International Publisher |
record_format | MEDLINE/PubMed |
spelling | pubmed-101979402023-05-20 Role of Exosomes in the Invasion and Metastasis of Ovarian Cancer and Application Potential of Clinical Diagnosis and Treatment Zhu, Yifei Wang, Cheng Ma, Ziyu Li, Feifei Xu, Chunwei Pan, Weiwei Liu, Aijun J Cancer Review Ovarian cancer is a highly lethal form of cancer in females, largely due to extensive metastases that often accompany the initial diagnosis. Exosomes are microvesicles size from 30 to 100nm, which can be secreted by most cells. These special extracellular vesicles play a vital role in the metastasis of ovarian cancer. In this study, we conducted a comprehensive review of current research pertaining to the role of exosomes in ovarian cancer, utilizing the PubMed(®) and Web of Science databases. Our review highlights the progress in elucidating the mechanisms by which exosomes facilitate ovarian cancer progression. Additionally, we discuss the potential of exosomes as a novel therapeutic target for ovarian cancer treatment. Overall, our review provides valuable insights into the current state of research on exosomes in ovarian cancer therapy. Ivyspring International Publisher 2023-04-17 /pmc/articles/PMC10197940/ /pubmed/37215442 http://dx.doi.org/10.7150/jca.83663 Text en © The author(s) https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions. |
spellingShingle | Review Zhu, Yifei Wang, Cheng Ma, Ziyu Li, Feifei Xu, Chunwei Pan, Weiwei Liu, Aijun Role of Exosomes in the Invasion and Metastasis of Ovarian Cancer and Application Potential of Clinical Diagnosis and Treatment |
title | Role of Exosomes in the Invasion and Metastasis of Ovarian Cancer and Application Potential of Clinical Diagnosis and Treatment |
title_full | Role of Exosomes in the Invasion and Metastasis of Ovarian Cancer and Application Potential of Clinical Diagnosis and Treatment |
title_fullStr | Role of Exosomes in the Invasion and Metastasis of Ovarian Cancer and Application Potential of Clinical Diagnosis and Treatment |
title_full_unstemmed | Role of Exosomes in the Invasion and Metastasis of Ovarian Cancer and Application Potential of Clinical Diagnosis and Treatment |
title_short | Role of Exosomes in the Invasion and Metastasis of Ovarian Cancer and Application Potential of Clinical Diagnosis and Treatment |
title_sort | role of exosomes in the invasion and metastasis of ovarian cancer and application potential of clinical diagnosis and treatment |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197940/ https://www.ncbi.nlm.nih.gov/pubmed/37215442 http://dx.doi.org/10.7150/jca.83663 |
work_keys_str_mv | AT zhuyifei roleofexosomesintheinvasionandmetastasisofovariancancerandapplicationpotentialofclinicaldiagnosisandtreatment AT wangcheng roleofexosomesintheinvasionandmetastasisofovariancancerandapplicationpotentialofclinicaldiagnosisandtreatment AT maziyu roleofexosomesintheinvasionandmetastasisofovariancancerandapplicationpotentialofclinicaldiagnosisandtreatment AT lifeifei roleofexosomesintheinvasionandmetastasisofovariancancerandapplicationpotentialofclinicaldiagnosisandtreatment AT xuchunwei roleofexosomesintheinvasionandmetastasisofovariancancerandapplicationpotentialofclinicaldiagnosisandtreatment AT panweiwei roleofexosomesintheinvasionandmetastasisofovariancancerandapplicationpotentialofclinicaldiagnosisandtreatment AT liuaijun roleofexosomesintheinvasionandmetastasisofovariancancerandapplicationpotentialofclinicaldiagnosisandtreatment |