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Role of Exosomes in the Invasion and Metastasis of Ovarian Cancer and Application Potential of Clinical Diagnosis and Treatment

Ovarian cancer is a highly lethal form of cancer in females, largely due to extensive metastases that often accompany the initial diagnosis. Exosomes are microvesicles size from 30 to 100nm, which can be secreted by most cells. These special extracellular vesicles play a vital role in the metastasis...

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Autores principales: Zhu, Yifei, Wang, Cheng, Ma, Ziyu, Li, Feifei, Xu, Chunwei, Pan, Weiwei, Liu, Aijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197940/
https://www.ncbi.nlm.nih.gov/pubmed/37215442
http://dx.doi.org/10.7150/jca.83663
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author Zhu, Yifei
Wang, Cheng
Ma, Ziyu
Li, Feifei
Xu, Chunwei
Pan, Weiwei
Liu, Aijun
author_facet Zhu, Yifei
Wang, Cheng
Ma, Ziyu
Li, Feifei
Xu, Chunwei
Pan, Weiwei
Liu, Aijun
author_sort Zhu, Yifei
collection PubMed
description Ovarian cancer is a highly lethal form of cancer in females, largely due to extensive metastases that often accompany the initial diagnosis. Exosomes are microvesicles size from 30 to 100nm, which can be secreted by most cells. These special extracellular vesicles play a vital role in the metastasis of ovarian cancer. In this study, we conducted a comprehensive review of current research pertaining to the role of exosomes in ovarian cancer, utilizing the PubMed(®) and Web of Science databases. Our review highlights the progress in elucidating the mechanisms by which exosomes facilitate ovarian cancer progression. Additionally, we discuss the potential of exosomes as a novel therapeutic target for ovarian cancer treatment. Overall, our review provides valuable insights into the current state of research on exosomes in ovarian cancer therapy.
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spelling pubmed-101979402023-05-20 Role of Exosomes in the Invasion and Metastasis of Ovarian Cancer and Application Potential of Clinical Diagnosis and Treatment Zhu, Yifei Wang, Cheng Ma, Ziyu Li, Feifei Xu, Chunwei Pan, Weiwei Liu, Aijun J Cancer Review Ovarian cancer is a highly lethal form of cancer in females, largely due to extensive metastases that often accompany the initial diagnosis. Exosomes are microvesicles size from 30 to 100nm, which can be secreted by most cells. These special extracellular vesicles play a vital role in the metastasis of ovarian cancer. In this study, we conducted a comprehensive review of current research pertaining to the role of exosomes in ovarian cancer, utilizing the PubMed(®) and Web of Science databases. Our review highlights the progress in elucidating the mechanisms by which exosomes facilitate ovarian cancer progression. Additionally, we discuss the potential of exosomes as a novel therapeutic target for ovarian cancer treatment. Overall, our review provides valuable insights into the current state of research on exosomes in ovarian cancer therapy. Ivyspring International Publisher 2023-04-17 /pmc/articles/PMC10197940/ /pubmed/37215442 http://dx.doi.org/10.7150/jca.83663 Text en © The author(s) https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions.
spellingShingle Review
Zhu, Yifei
Wang, Cheng
Ma, Ziyu
Li, Feifei
Xu, Chunwei
Pan, Weiwei
Liu, Aijun
Role of Exosomes in the Invasion and Metastasis of Ovarian Cancer and Application Potential of Clinical Diagnosis and Treatment
title Role of Exosomes in the Invasion and Metastasis of Ovarian Cancer and Application Potential of Clinical Diagnosis and Treatment
title_full Role of Exosomes in the Invasion and Metastasis of Ovarian Cancer and Application Potential of Clinical Diagnosis and Treatment
title_fullStr Role of Exosomes in the Invasion and Metastasis of Ovarian Cancer and Application Potential of Clinical Diagnosis and Treatment
title_full_unstemmed Role of Exosomes in the Invasion and Metastasis of Ovarian Cancer and Application Potential of Clinical Diagnosis and Treatment
title_short Role of Exosomes in the Invasion and Metastasis of Ovarian Cancer and Application Potential of Clinical Diagnosis and Treatment
title_sort role of exosomes in the invasion and metastasis of ovarian cancer and application potential of clinical diagnosis and treatment
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197940/
https://www.ncbi.nlm.nih.gov/pubmed/37215442
http://dx.doi.org/10.7150/jca.83663
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