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Differentiation of imatinib -resistant chronic myeloid leukemia cells with BCR-ABL-T315I mutation induced by Jiyuan Oridonin A

Chronic myeloid leukemia (CML) results from BCR-ABL oncogene, which blocks CML cells differentiation and protects these cells from apoptosis. T315I mutated BCR-ABL is the main cause of the resistance mediated by imatinib and second generation BCR-ABL inhibitor. CML with the T315I mutation has been c...

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Detalles Bibliográficos
Autores principales:	Xu, Yun, Wang, Ziting, Zhang, Lei, Gao, Congying, Li, Fahui, Li, Xueming, Ke, Yu, Liu, Hong-Min, Hu, Zhenbo, Wei, Liuya, Chen, Zhe-Sheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2023
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10197941/ https://www.ncbi.nlm.nih.gov/pubmed/37215441 http://dx.doi.org/10.7150/jca.83219

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