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LY294002 alleviates bone cancer pain by reducing mitochondrial dysfunction and the inflammatory response
Bone cancer pain (BCP) is mainly caused by bone metastasis and markedly impairs the functional capacity and daily functions of patients. Neuroinflammation plays a pivotal role in the pathogenesis and maintenance of chronic pain. Oxidative stress in the mitochondria is a key contributor to neuroinfla...
Autores principales: | Zhao, Jiajia, Yan, Ying, Zhen, Shuqing, Yu, Liangzhu, Ding, Jieqiong, Tang, Qiong, Liu, Ling, Zhu, Haili, Xie, Min |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198047/ https://www.ncbi.nlm.nih.gov/pubmed/37026522 http://dx.doi.org/10.3892/ijmm.2023.5245 |
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