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LY294002 alleviates bone cancer pain by reducing mitochondrial dysfunction and the inflammatory response

Bone cancer pain (BCP) is mainly caused by bone metastasis and markedly impairs the functional capacity and daily functions of patients. Neuroinflammation plays a pivotal role in the pathogenesis and maintenance of chronic pain. Oxidative stress in the mitochondria is a key contributor to neuroinfla...

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Detalles Bibliográficos
Autores principales: Zhao, Jiajia, Yan, Ying, Zhen, Shuqing, Yu, Liangzhu, Ding, Jieqiong, Tang, Qiong, Liu, Ling, Zhu, Haili, Xie, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198047/
https://www.ncbi.nlm.nih.gov/pubmed/37026522
http://dx.doi.org/10.3892/ijmm.2023.5245

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