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A rare case of “Brown tumor” of the axis with parathyroid adenoma and tertiary hyperparathyroidism

“Brown tumors (BTs)” of the spine are benign rare lesions, seen in about 5%–13% of all patients with chronic hyperparathyroidism (HPT). They are not true neoplasms and are also known as osteitis fibrosa cystica or occasionally osteoclastoma. Radiological presentations are often misleading and may mi...

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Autores principales: Srikantha, Umesh, Hari, Akshay, Lokanath, Yadhu K, Mahesh, D. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198211/
https://www.ncbi.nlm.nih.gov/pubmed/37213580
http://dx.doi.org/10.4103/jcvjs.jcvjs_144_22
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author Srikantha, Umesh
Hari, Akshay
Lokanath, Yadhu K
Mahesh, D. M.
author_facet Srikantha, Umesh
Hari, Akshay
Lokanath, Yadhu K
Mahesh, D. M.
author_sort Srikantha, Umesh
collection PubMed
description “Brown tumors (BTs)” of the spine are benign rare lesions, seen in about 5%–13% of all patients with chronic hyperparathyroidism (HPT). They are not true neoplasms and are also known as osteitis fibrosa cystica or occasionally osteoclastoma. Radiological presentations are often misleading and may mimic other common lesions such as metastasis. A strong clinical suspicion is therefore necessary, especially in the background of chronic kidney disease with HPT and parathyroid adenoma. Surgical spinal fixation in case of instability due to pathological fracture may be required along with excision of the parathyroid adenoma being the treatment of choice, that maybe usually curative and carries a good prognosis. We would like to report one such rare case of BT involving the axis, or C2 vertebra, presenting with neck pain and weakness that was treated surgically. Only a few cases of spinal BTs have been reported so far in the literature. Involvement of cervical vertebrae and in particular C2 is rarer still with the one in this report only being the fourth such case.
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spelling pubmed-101982112023-05-20 A rare case of “Brown tumor” of the axis with parathyroid adenoma and tertiary hyperparathyroidism Srikantha, Umesh Hari, Akshay Lokanath, Yadhu K Mahesh, D. M. J Craniovertebr Junction Spine Case Report “Brown tumors (BTs)” of the spine are benign rare lesions, seen in about 5%–13% of all patients with chronic hyperparathyroidism (HPT). They are not true neoplasms and are also known as osteitis fibrosa cystica or occasionally osteoclastoma. Radiological presentations are often misleading and may mimic other common lesions such as metastasis. A strong clinical suspicion is therefore necessary, especially in the background of chronic kidney disease with HPT and parathyroid adenoma. Surgical spinal fixation in case of instability due to pathological fracture may be required along with excision of the parathyroid adenoma being the treatment of choice, that maybe usually curative and carries a good prognosis. We would like to report one such rare case of BT involving the axis, or C2 vertebra, presenting with neck pain and weakness that was treated surgically. Only a few cases of spinal BTs have been reported so far in the literature. Involvement of cervical vertebrae and in particular C2 is rarer still with the one in this report only being the fourth such case. Wolters Kluwer - Medknow 2023 2023-03-13 /pmc/articles/PMC10198211/ /pubmed/37213580 http://dx.doi.org/10.4103/jcvjs.jcvjs_144_22 Text en Copyright: © 2023 Journal of Craniovertebral Junction and Spine https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Srikantha, Umesh
Hari, Akshay
Lokanath, Yadhu K
Mahesh, D. M.
A rare case of “Brown tumor” of the axis with parathyroid adenoma and tertiary hyperparathyroidism
title A rare case of “Brown tumor” of the axis with parathyroid adenoma and tertiary hyperparathyroidism
title_full A rare case of “Brown tumor” of the axis with parathyroid adenoma and tertiary hyperparathyroidism
title_fullStr A rare case of “Brown tumor” of the axis with parathyroid adenoma and tertiary hyperparathyroidism
title_full_unstemmed A rare case of “Brown tumor” of the axis with parathyroid adenoma and tertiary hyperparathyroidism
title_short A rare case of “Brown tumor” of the axis with parathyroid adenoma and tertiary hyperparathyroidism
title_sort rare case of “brown tumor” of the axis with parathyroid adenoma and tertiary hyperparathyroidism
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198211/
https://www.ncbi.nlm.nih.gov/pubmed/37213580
http://dx.doi.org/10.4103/jcvjs.jcvjs_144_22
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