A Targeted, Low-Throughput Compound Screen in a Drosophila Model of Neurofibromatosis Type 1 Identifies Simvastatin and BMS-204352 as Potential Therapies for Autism Spectrum Disorder (ASD)

Autism spectrum disorder (ASD) is a common neurodevelopmental condition for which there are no pharmacological therapies that effectively target its core symptomatology. Animal models of syndromic forms of ASD, such as neurofibromatosis type 1, may be of use in screening for such treatments. Drosoph...

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Detalles Bibliográficos
Autores principales: Dyson, Alex, Ryan, Megan, Garg, Shruti, Evans, D. Gareth, Baines, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2023
Materias:
Research Article: New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198605/
https://www.ncbi.nlm.nih.gov/pubmed/37185294
http://dx.doi.org/10.1523/ENEURO.0461-22.2023

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