Cargando…

Nociceptor activity induces nonionotropic NMDA receptor signaling to enable spinal reconsolidation and reverse pathological pain

Chronic, pathological pain is a highly debilitating condition that can arise and be maintained through central sensitization. Central sensitization shares mechanistic and phenotypic parallels with memory formation. In a sensory model of memory reconsolidation, plastic changes underlying pain hyperse...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Hantao, Rodriguez-Hernandez, Luis D., D’Souza, Abigail J., He, David, Zain, Maham, Fung, Samuel W., Bennett, Laura A., Bonin, Robert P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198626/
https://www.ncbi.nlm.nih.gov/pubmed/37205760
http://dx.doi.org/10.1126/sciadv.adg2819