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Nociceptor activity induces nonionotropic NMDA receptor signaling to enable spinal reconsolidation and reverse pathological pain
Chronic, pathological pain is a highly debilitating condition that can arise and be maintained through central sensitization. Central sensitization shares mechanistic and phenotypic parallels with memory formation. In a sensory model of memory reconsolidation, plastic changes underlying pain hyperse...
Autores principales: | Zhang, Hantao, Rodriguez-Hernandez, Luis D., D’Souza, Abigail J., He, David, Zain, Maham, Fung, Samuel W., Bennett, Laura A., Bonin, Robert P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198626/ https://www.ncbi.nlm.nih.gov/pubmed/37205760 http://dx.doi.org/10.1126/sciadv.adg2819 |
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