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Nanoscale clustering of mycobacterial ligands and DC-SIGN host receptors are key determinants for pathogen recognition

The bacterial pathogen Mycobacterium tuberculosis binds to the C-type lectin DC-SIGN (dendritic cell–specific intercellular adhesion molecule 3-grabbing nonintegrin) on dendritic cells to evade the immune system. While DC-SIGN glycoconjugate ligands are ubiquitous among mycobacterial species, the re...

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Detalles Bibliográficos
Autores principales:	Viljoen, Albertus, Vercellone, Alain, Chimen, Myriam, Gaibelet, Gérald, Mazères, Serge, Nigou, Jérôme, Dufrêne, Yves F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2023
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198640/ https://www.ncbi.nlm.nih.gov/pubmed/37205764 http://dx.doi.org/10.1126/sciadv.adf9498

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