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Deletion of p75(NTR) rescues the synaptic but not the inflammatory status in the brain of a mouse model for Alzheimer’s disease
INTRODUCTION: Alzheimer’s disease (AD), is characterized by a gradual cognitive decline associated with the accumulation of Amyloid beta (Aβ)-oligomers, progressive neuronal degeneration and chronic neuroinflammation. Among the receptors shown to bind and possibly transduce the toxic effects of Aβ-o...
Autores principales: | Demuth, Hendrik, Hosseini, Shirin, Düsedeau, Henning Peter, Dunay, Ildiko Rita, Korte, Martin, Zagrebelsky, Marta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198655/ https://www.ncbi.nlm.nih.gov/pubmed/37213691 http://dx.doi.org/10.3389/fnmol.2023.1163087 |
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