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Alterations in the megakaryocyte transcriptome impacts platelet function in sepsis and COVID-19 infection

Platelets and their parent cell, the megakaryocyte (MK), are increasingly recognized for their roles during infection and inflammation. The MK residing in the bone marrow or arising from precursors trafficked to other organs for development go on to form platelets through thrombopoiesis. Infection,...

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Detalles Bibliográficos
Autores principales: Ajanel, Abigail, Middleton, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198739/
https://www.ncbi.nlm.nih.gov/pubmed/37258336
http://dx.doi.org/10.1016/j.thromres.2023.05.015