Effects of the STAMP-inhibitor asciminib on T cell activation and metabolic fitness compared to tyrosine kinase inhibition by imatinib, dasatinib, and nilotinib

T cell function is central to immune reconstitution and control of residual chronic myeloid leukemia (CML) cells after treatment initiation and is associated with achieving deep molecular response as a prerequisite for treatment-free remission, the ultimate therapeutic goal in CML. ATP-pocket-bindin...

Descripción completa

Detalles Bibliográficos
Autores principales: Häselbarth, Lukas, Karow, Axel, Mentz, Kristin, Böttcher, Martin, Roche-Lancaster, Oisin, Krumbholz, Manuela, Jitschin, Regina, Mougiakakos, Dimitrios, Metzler, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198838/
https://www.ncbi.nlm.nih.gov/pubmed/36602564
http://dx.doi.org/10.1007/s00262-022-03361-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198838/
https://www.ncbi.nlm.nih.gov/pubmed/36602564
http://dx.doi.org/10.1007/s00262-022-03361-8

Ejemplares similares