Endosialin-positive tumor-derived pericytes promote tumor progression through impeding the infiltration of CD8(+) T cells in clear cell renal cell carcinoma

BACKGROUND: Immune checkpoint blockade (ICB) therapy can be effective against clear cell renal cell carcinoma (ccRCC), but many patients show no benefit. Tumor-derived pericytes (TDPs) may promote tumor progression by influencing T cells and are an immunotherapy target; however, they may comprise fu...

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Detalles Bibliográficos
Autores principales: Lu, Tong, Zhang, Jiayu, Lu, Shiqi, Yang, Fa, Gan, Lunbiao, Wu, Xinjie, Song, Hongtao, Liu, Shaojie, Xu, Chao, Han, Donghui, Yang, Bo, Wen, Weihong, Qin, Weijun, Yang, Lijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198862/
https://www.ncbi.nlm.nih.gov/pubmed/36646951
http://dx.doi.org/10.1007/s00262-023-03372-z

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