Overexpression of VIRMA confers vulnerability to breast cancers via the m(6)A-dependent regulation of unfolded protein response

Virilizer-like m(6)A methyltransferase-associated protein (VIRMA) maintains the stability of the m(6)A writer complex. Although VIRMA is critical for RNA m(6)A deposition, the impact of aberrant VIRMA expression in human diseases remains unclear. We show that VIRMA is amplified and overexpressed in...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Quintin, Song, Renhua, Phan, Dang Anh Vu, Pinello, Natalia, Tieng, Jessica, Su, Anni, Halstead, James M., Wong, Alex C. H., van Geldermalsen, Michelle, Lee, Bob S.-L., Rong, Bowen, Cook, Kristina M., Larance, Mark, Liu, Renjing, Lan, Fei, Tiffen, Jessamy C., Wong, Justin J.-L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198946/
https://www.ncbi.nlm.nih.gov/pubmed/37208522
http://dx.doi.org/10.1007/s00018-023-04799-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198946/
https://www.ncbi.nlm.nih.gov/pubmed/37208522
http://dx.doi.org/10.1007/s00018-023-04799-4

Ejemplares similares