Unidirectional rotation of micromotors on water powered by pH-controlled disassembly of chiral molecular crystals

Biological and synthetic molecular motors, fueled by various physical and chemical means, can perform asymmetric linear and rotary motions that are inherently related to their asymmetric shapes. Here, we describe silver-organic micro-complexes of random shapes that exhibit macroscopic unidirectional...

Descripción completa

Detalles Bibliográficos
Autores principales: Carmeli, Itai, Bounioux, Celine M., Mickel, Philip, Richardson, Mark B., Templeman, Yael, Scofield, Joel M. P., Qiao, Greg G., Rosen, Brian Ashley, Yusupov, Yelena, Meshi, Louisa, Voelcker, Nicolas H., Diéguez, Oswaldo, Miloh, Touvia, Král, Petr, Cohen, Hagai, Richter, Shachar E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198998/
https://www.ncbi.nlm.nih.gov/pubmed/37208331
http://dx.doi.org/10.1038/s41467-023-38308-9
_version_ 1785044837390614528
author Carmeli, Itai
Bounioux, Celine M.
Mickel, Philip
Richardson, Mark B.
Templeman, Yael
Scofield, Joel M. P.
Qiao, Greg G.
Rosen, Brian Ashley
Yusupov, Yelena
Meshi, Louisa
Voelcker, Nicolas H.
Diéguez, Oswaldo
Miloh, Touvia
Král, Petr
Cohen, Hagai
Richter, Shachar E.
author_facet Carmeli, Itai
Bounioux, Celine M.
Mickel, Philip
Richardson, Mark B.
Templeman, Yael
Scofield, Joel M. P.
Qiao, Greg G.
Rosen, Brian Ashley
Yusupov, Yelena
Meshi, Louisa
Voelcker, Nicolas H.
Diéguez, Oswaldo
Miloh, Touvia
Král, Petr
Cohen, Hagai
Richter, Shachar E.
author_sort Carmeli, Itai
collection PubMed
description Biological and synthetic molecular motors, fueled by various physical and chemical means, can perform asymmetric linear and rotary motions that are inherently related to their asymmetric shapes. Here, we describe silver-organic micro-complexes of random shapes that exhibit macroscopic unidirectional rotation on water surface through the asymmetric release of cinchonine or cinchonidine chiral molecules from their crystallites asymmetrically adsorbed on the complex surfaces. Computational modeling indicates that the motor rotation is driven by a pH-controlled asymmetric jet-like Coulombic ejection of chiral molecules upon their protonation in water. The motor is capable of towing very large cargo, and its rotation can be accelerated by adding reducing agents to the water.
format Online
Article
Text
id pubmed-10198998
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-101989982023-05-21 Unidirectional rotation of micromotors on water powered by pH-controlled disassembly of chiral molecular crystals Carmeli, Itai Bounioux, Celine M. Mickel, Philip Richardson, Mark B. Templeman, Yael Scofield, Joel M. P. Qiao, Greg G. Rosen, Brian Ashley Yusupov, Yelena Meshi, Louisa Voelcker, Nicolas H. Diéguez, Oswaldo Miloh, Touvia Král, Petr Cohen, Hagai Richter, Shachar E. Nat Commun Article Biological and synthetic molecular motors, fueled by various physical and chemical means, can perform asymmetric linear and rotary motions that are inherently related to their asymmetric shapes. Here, we describe silver-organic micro-complexes of random shapes that exhibit macroscopic unidirectional rotation on water surface through the asymmetric release of cinchonine or cinchonidine chiral molecules from their crystallites asymmetrically adsorbed on the complex surfaces. Computational modeling indicates that the motor rotation is driven by a pH-controlled asymmetric jet-like Coulombic ejection of chiral molecules upon their protonation in water. The motor is capable of towing very large cargo, and its rotation can be accelerated by adding reducing agents to the water. Nature Publishing Group UK 2023-05-19 /pmc/articles/PMC10198998/ /pubmed/37208331 http://dx.doi.org/10.1038/s41467-023-38308-9 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Carmeli, Itai
Bounioux, Celine M.
Mickel, Philip
Richardson, Mark B.
Templeman, Yael
Scofield, Joel M. P.
Qiao, Greg G.
Rosen, Brian Ashley
Yusupov, Yelena
Meshi, Louisa
Voelcker, Nicolas H.
Diéguez, Oswaldo
Miloh, Touvia
Král, Petr
Cohen, Hagai
Richter, Shachar E.
Unidirectional rotation of micromotors on water powered by pH-controlled disassembly of chiral molecular crystals
title Unidirectional rotation of micromotors on water powered by pH-controlled disassembly of chiral molecular crystals
title_full Unidirectional rotation of micromotors on water powered by pH-controlled disassembly of chiral molecular crystals
title_fullStr Unidirectional rotation of micromotors on water powered by pH-controlled disassembly of chiral molecular crystals
title_full_unstemmed Unidirectional rotation of micromotors on water powered by pH-controlled disassembly of chiral molecular crystals
title_short Unidirectional rotation of micromotors on water powered by pH-controlled disassembly of chiral molecular crystals
title_sort unidirectional rotation of micromotors on water powered by ph-controlled disassembly of chiral molecular crystals
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198998/
https://www.ncbi.nlm.nih.gov/pubmed/37208331
http://dx.doi.org/10.1038/s41467-023-38308-9
work_keys_str_mv AT carmeliitai unidirectionalrotationofmicromotorsonwaterpoweredbyphcontrolleddisassemblyofchiralmolecularcrystals
AT bouniouxcelinem unidirectionalrotationofmicromotorsonwaterpoweredbyphcontrolleddisassemblyofchiralmolecularcrystals
AT mickelphilip unidirectionalrotationofmicromotorsonwaterpoweredbyphcontrolleddisassemblyofchiralmolecularcrystals
AT richardsonmarkb unidirectionalrotationofmicromotorsonwaterpoweredbyphcontrolleddisassemblyofchiralmolecularcrystals
AT templemanyael unidirectionalrotationofmicromotorsonwaterpoweredbyphcontrolleddisassemblyofchiralmolecularcrystals
AT scofieldjoelmp unidirectionalrotationofmicromotorsonwaterpoweredbyphcontrolleddisassemblyofchiralmolecularcrystals
AT qiaogregg unidirectionalrotationofmicromotorsonwaterpoweredbyphcontrolleddisassemblyofchiralmolecularcrystals
AT rosenbrianashley unidirectionalrotationofmicromotorsonwaterpoweredbyphcontrolleddisassemblyofchiralmolecularcrystals
AT yusupovyelena unidirectionalrotationofmicromotorsonwaterpoweredbyphcontrolleddisassemblyofchiralmolecularcrystals
AT meshilouisa unidirectionalrotationofmicromotorsonwaterpoweredbyphcontrolleddisassemblyofchiralmolecularcrystals
AT voelckernicolash unidirectionalrotationofmicromotorsonwaterpoweredbyphcontrolleddisassemblyofchiralmolecularcrystals
AT dieguezoswaldo unidirectionalrotationofmicromotorsonwaterpoweredbyphcontrolleddisassemblyofchiralmolecularcrystals
AT milohtouvia unidirectionalrotationofmicromotorsonwaterpoweredbyphcontrolleddisassemblyofchiralmolecularcrystals
AT kralpetr unidirectionalrotationofmicromotorsonwaterpoweredbyphcontrolleddisassemblyofchiralmolecularcrystals
AT cohenhagai unidirectionalrotationofmicromotorsonwaterpoweredbyphcontrolleddisassemblyofchiralmolecularcrystals
AT richtershachare unidirectionalrotationofmicromotorsonwaterpoweredbyphcontrolleddisassemblyofchiralmolecularcrystals