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Biophotonic sensor for swift detection of malignant brain tissues by using nanocomposite YBa(2)Cu(3)O(7)/dielectric material as a 1D defective photonic crystal
In the present research work we have theoretically examined the biosensing capabilities of proposed one dimensional defective photonic crystal for swift detection of malignant brain tissues. The transfer matrix formulation and MATLAB computational tool have been used to examine the transmission prop...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199004/ https://www.ncbi.nlm.nih.gov/pubmed/37208397 http://dx.doi.org/10.1038/s41598-023-34601-1 |
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author | Malek, C. Abdallah, Suhad Ali Osman Awasthi, S. K. Ismail, M. A. Sabra, W. Aly, Arafa H. |
author_facet | Malek, C. Abdallah, Suhad Ali Osman Awasthi, S. K. Ismail, M. A. Sabra, W. Aly, Arafa H. |
author_sort | Malek, C. |
collection | PubMed |
description | In the present research work we have theoretically examined the biosensing capabilities of proposed one dimensional defective photonic crystal for swift detection of malignant brain tissues. The transfer matrix formulation and MATLAB computational tool have been used to examine the transmission properties of proposed structure. The identical buffer layers of nanocomposite superconducting material have been used either side of cavity region to enhance the interaction between incident light and different brain tissue samples poured into the cavity region. All the investigations have been carried out under normal incidence to suppress the experimental liabilities involved. We have investigated the biosensing performance of the proposed design by changing the values of two internal parameters (1) the cavity layer thickness (d(4)) and (2) volume fraction (η) of nanocomposite buffer layers one by one to get the optimum biosensing performance from the structure. It has been found that the sensitivity of the proposed design becomes 1.42607 μm/RIU when the cavity region of thickness 15dd is loaded with lymphoma brain tissue. This value of sensitivity can be further increased to 2.66136 μm/RIU with η = 0.8. The findings of this work are very beneficial for designing of various bio-sensing structures composed of nanocomposite materials of diversified biomedical applications. |
format | Online Article Text |
id | pubmed-10199004 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-101990042023-05-21 Biophotonic sensor for swift detection of malignant brain tissues by using nanocomposite YBa(2)Cu(3)O(7)/dielectric material as a 1D defective photonic crystal Malek, C. Abdallah, Suhad Ali Osman Awasthi, S. K. Ismail, M. A. Sabra, W. Aly, Arafa H. Sci Rep Article In the present research work we have theoretically examined the biosensing capabilities of proposed one dimensional defective photonic crystal for swift detection of malignant brain tissues. The transfer matrix formulation and MATLAB computational tool have been used to examine the transmission properties of proposed structure. The identical buffer layers of nanocomposite superconducting material have been used either side of cavity region to enhance the interaction between incident light and different brain tissue samples poured into the cavity region. All the investigations have been carried out under normal incidence to suppress the experimental liabilities involved. We have investigated the biosensing performance of the proposed design by changing the values of two internal parameters (1) the cavity layer thickness (d(4)) and (2) volume fraction (η) of nanocomposite buffer layers one by one to get the optimum biosensing performance from the structure. It has been found that the sensitivity of the proposed design becomes 1.42607 μm/RIU when the cavity region of thickness 15dd is loaded with lymphoma brain tissue. This value of sensitivity can be further increased to 2.66136 μm/RIU with η = 0.8. The findings of this work are very beneficial for designing of various bio-sensing structures composed of nanocomposite materials of diversified biomedical applications. Nature Publishing Group UK 2023-05-19 /pmc/articles/PMC10199004/ /pubmed/37208397 http://dx.doi.org/10.1038/s41598-023-34601-1 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Malek, C. Abdallah, Suhad Ali Osman Awasthi, S. K. Ismail, M. A. Sabra, W. Aly, Arafa H. Biophotonic sensor for swift detection of malignant brain tissues by using nanocomposite YBa(2)Cu(3)O(7)/dielectric material as a 1D defective photonic crystal |
title | Biophotonic sensor for swift detection of malignant brain tissues by using nanocomposite YBa(2)Cu(3)O(7)/dielectric material as a 1D defective photonic crystal |
title_full | Biophotonic sensor for swift detection of malignant brain tissues by using nanocomposite YBa(2)Cu(3)O(7)/dielectric material as a 1D defective photonic crystal |
title_fullStr | Biophotonic sensor for swift detection of malignant brain tissues by using nanocomposite YBa(2)Cu(3)O(7)/dielectric material as a 1D defective photonic crystal |
title_full_unstemmed | Biophotonic sensor for swift detection of malignant brain tissues by using nanocomposite YBa(2)Cu(3)O(7)/dielectric material as a 1D defective photonic crystal |
title_short | Biophotonic sensor for swift detection of malignant brain tissues by using nanocomposite YBa(2)Cu(3)O(7)/dielectric material as a 1D defective photonic crystal |
title_sort | biophotonic sensor for swift detection of malignant brain tissues by using nanocomposite yba(2)cu(3)o(7)/dielectric material as a 1d defective photonic crystal |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199004/ https://www.ncbi.nlm.nih.gov/pubmed/37208397 http://dx.doi.org/10.1038/s41598-023-34601-1 |
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