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A nomogram to predict postoperative surgical site infection of adult patients who received orthopaedic surgery: a retrospective study

Surgical site infection is a common postoperative complication with serious consequences. This study developed a nomogram to estimate the probability of postoperative surgical site infection for orthopaedic patients. Adult patients following orthopaedic surgery during hospitalization were included i...

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Autores principales: Huang, Xu’an, Guo, Yang, Fu, Ribin, Li, Hongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199048/
https://www.ncbi.nlm.nih.gov/pubmed/37208366
http://dx.doi.org/10.1038/s41598-023-34926-x
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author Huang, Xu’an
Guo, Yang
Fu, Ribin
Li, Hongwei
author_facet Huang, Xu’an
Guo, Yang
Fu, Ribin
Li, Hongwei
author_sort Huang, Xu’an
collection PubMed
description Surgical site infection is a common postoperative complication with serious consequences. This study developed a nomogram to estimate the probability of postoperative surgical site infection for orthopaedic patients. Adult patients following orthopaedic surgery during hospitalization were included in this study. We used univariate and multivariate logistic regression analyses to establish the predictive model, which was also visualized by nomogram. To evaluate the model performance, we applied the receiver operating characteristic curve, calibration curve, and decision curve analysis, which were utilized in external validation and internal validation. From January 2021 to June 2022, a total of 787 patients were enrolled in this study. After statistical analysis, five variables were enrolled in the predictive model, including age, operation time, diabetes, WBC, and HGB. The mathematical formula has been established as follows: Logit (SSI) = − 6.301 + 1.104 * (Age) + 0.669 * (Operation time) + 2.009 * (Diabetes) + 1.520 * (WBC) − 1.119 * (HGB). The receiver Operating Characteristic curve, calibration curve, and decision curve analysis presented a good performance of this predictive model. Our nomogram showed great discriminative ability, calibration, and clinical practicability in the training set, external validation, and internal validation.
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spelling pubmed-101990482023-05-21 A nomogram to predict postoperative surgical site infection of adult patients who received orthopaedic surgery: a retrospective study Huang, Xu’an Guo, Yang Fu, Ribin Li, Hongwei Sci Rep Article Surgical site infection is a common postoperative complication with serious consequences. This study developed a nomogram to estimate the probability of postoperative surgical site infection for orthopaedic patients. Adult patients following orthopaedic surgery during hospitalization were included in this study. We used univariate and multivariate logistic regression analyses to establish the predictive model, which was also visualized by nomogram. To evaluate the model performance, we applied the receiver operating characteristic curve, calibration curve, and decision curve analysis, which were utilized in external validation and internal validation. From January 2021 to June 2022, a total of 787 patients were enrolled in this study. After statistical analysis, five variables were enrolled in the predictive model, including age, operation time, diabetes, WBC, and HGB. The mathematical formula has been established as follows: Logit (SSI) = − 6.301 + 1.104 * (Age) + 0.669 * (Operation time) + 2.009 * (Diabetes) + 1.520 * (WBC) − 1.119 * (HGB). The receiver Operating Characteristic curve, calibration curve, and decision curve analysis presented a good performance of this predictive model. Our nomogram showed great discriminative ability, calibration, and clinical practicability in the training set, external validation, and internal validation. Nature Publishing Group UK 2023-05-19 /pmc/articles/PMC10199048/ /pubmed/37208366 http://dx.doi.org/10.1038/s41598-023-34926-x Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Huang, Xu’an
Guo, Yang
Fu, Ribin
Li, Hongwei
A nomogram to predict postoperative surgical site infection of adult patients who received orthopaedic surgery: a retrospective study
title A nomogram to predict postoperative surgical site infection of adult patients who received orthopaedic surgery: a retrospective study
title_full A nomogram to predict postoperative surgical site infection of adult patients who received orthopaedic surgery: a retrospective study
title_fullStr A nomogram to predict postoperative surgical site infection of adult patients who received orthopaedic surgery: a retrospective study
title_full_unstemmed A nomogram to predict postoperative surgical site infection of adult patients who received orthopaedic surgery: a retrospective study
title_short A nomogram to predict postoperative surgical site infection of adult patients who received orthopaedic surgery: a retrospective study
title_sort nomogram to predict postoperative surgical site infection of adult patients who received orthopaedic surgery: a retrospective study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199048/
https://www.ncbi.nlm.nih.gov/pubmed/37208366
http://dx.doi.org/10.1038/s41598-023-34926-x
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