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Transcriptomic profiling of induced steatosis in human and mouse precision-cut liver slices

There is a high need for predictive human ex vivo models for non-alcoholic fatty liver disease (NAFLD). About a decade ago, precision-cut liver slices (PCLSs) have been established as an ex vivo assay for humans and other organisms. In the present study, we use transcriptomics by RNASeq to profile a...

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Detalles Bibliográficos
Autores principales: Simon, Eric, Motyka, Maciej, Prins, Grietje H., Li, Mei, Rust, Werner, Kauschke, Stefan, Viollet, Coralie, Olinga, Peter, Oldenburger, Anouk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199090/
https://www.ncbi.nlm.nih.gov/pubmed/37208356
http://dx.doi.org/10.1038/s41597-023-02220-0

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